Identification of Histone Epigenetic Modifications with Chromatin Immunoprecipitation PCR Array in Chronic Lymphocytic Leukemia Specimens
نویسندگان
چکیده
منابع مشابه
Identification of Histone Epigenetic Modifications with Chromatin Immunoprecipitation PCR Array in Chronic Lymphocytic Leukemia Specimens
Histone epigenetic modifications are one of the frequently observed epigenetic alterations in leukemic cells. To efficiently identify histone acetylation status of a number of gene promoters in chronic lymphocytic leukemia (CLL) specimens, we performed a combination of chromatin immunoprecipitation (ChIP) and PCR array. ChIP by an antipan acetylated H4 histone antibody was followed by a PCR amp...
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1Hôpital Pitié-Salpêtrière, Université Pierre et Marie Curie (UPMC) Paris VI, Inserm, Paris, France; 2CNRS UMR 3348, Institut Curie, Université Paris Sud-11, Orsay, France; 3Institut Cochin, Université Paris Descartes, CNRS, Paris, France, 4Inserm, Paris, France; 5Hôpital Pitié-Salpêtrière, Service d’Hématologie Biologique, Paris, France; and 6CDR des Cordeliers, UPMC Paris VI, Inserm, Paris, F...
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ژورنال
عنوان ژورنال: Journal of Cancer Science & Therapy
سال: 2014
ISSN: 1948-5956
DOI: 10.4172/1948-5956.1000290